Incidence of Significant Bacteriuria among Pregnant Women in a Teaching Hospital of Rural Setup
Aim: This study was carried out to determine the prevalence of asymptomatic bacteriuria in pregnant women attending a teaching hospital in rural setup. Materials and Methods: A total of 600 women were recruited for this study. A total of 200 antenatal women were clinically identified to have no signs and symptoms of UTI, 200 antenatal women were having signs and symptoms of UTI, and 200 were non-pregnant women that were studied as controls. Clean catch midstream urine samples were collected from each patient into a sterile universal container from Gynecology and obstetrics department and general medicine department. The urine samples were examined microscopically and by the cultural method. Identification of isolates was carried out by a standard microbiological technique. Result: A total of 272 (45.3%) were positive for significant bacteriuria. There was a significant difference in the prevalence of asymptomatic bacteriuria with respect to age (P< 0.0001). Trimester did not show any significant difference (P = 0.2006) in the prevalence of asymptomatic bacteriuria. Escherichia coli was the most predominant organism followed closely by Klebsiella species. Nitrofurantoin, ampicillin, and levofloxacin were mostly used antibiotics. Conclusion: Asymptomatic bacteriuria is not uncommon among antenatal patients in the population studied. Routine urine cultural test should be carried out on all antenatal patients in order to identify any unsuspecting infection. This measure will go a long way in reducing maternal and obstetric complications associated with pregnancy.
KEYWORDS: Asymptomatic bacteriuria, Antenatal women, Bacteriuria, Significant bacteriuria, Non pregnant women, Mid stream urine samples, Catheterized samples
Kriplaini A, Bukshe K, Ratan A. Asymptomatic bacteriuria in pregnant Indian patients at AIIMS, New Delhi and treatment with single dose antimicrobial therapy. J Obstet Gynecol India 1993;43:489–91.
Sharma JB et al. Prevalence of significant bacteria in preterm labour. J Obstet Gynecol India 1990;40:336– 8.
Wyngaarden JB, Smith LH, Bennett JC, editors. Cecil of Medicine. 19th ed. Philadelphia, PA: W.B. Saunders; 1992. pp. 593–7.
Connolly A, Thorp JM. Jnr urinary tract infection in pregnancy. Urol Clin North Am 1999;26(4):779–87.
Nicolle LE. Screening for asymptomatic bacteriuria in pregnancy. In: Canadian guide on preventive health care. Ottawa, Canada: Ottawa Health; 1994. pp. 100– 06.
Delzell JE, Leferre ML. Urinary tract infections during pregnancy. Am Fam Phys 2000;61(3):713–21.
Wolday D, Erge W. Increased incidence of resistance to antimicrobials by urinary pathogens isolated at Tikur Anbessa hospital. Ethiop Med J 1997;35(2):127– 35.
Olusanya O, Ogunledum A, Fakoya TA. Asymptomatic significant bacteriuria among pregnant and non-pregnant women in Sagamu,
Nigeria West. Afr J Med 1993;12(1):27–33.
Akerele P, Abhuliren F, Okonofua J. Prevalence of asymptomatic bacteriuria among pregnant women in Benin City, Nigeria. J Obstet Gynaecol 2001;21(2):141–4.
Dutta Obstretrics textbook page no. 297.
Pregnancy medical disorders Barron page no. 47.
Mond N-C, Grunebery RN, Smellie JM. A study of childhood urinary tract infection in general practice. Br Med J1970;1:602–5.
Barry AL, Thornberry C. Susceptibility tests: diffusion test procedures. In: Ballow A, et al., editors. Manual of clinical microbiology.5th ed. Washington D.C.: American Society for Microbiology; 1991. pp. 1117–25.
Cheesebrough M. District Laboratory Practice in tropical countries. Part 2. Cambridge, U.K.: Cambridge University Press; 2000. pp. 105–14.
Mackie and Mc Cartney diagnostic microbiology. Amsterdam, The Netherlands: Elsevier; 1996.
The National Committee for Clinical Laboratory Standard (NCCLS) operating procedure.
Bailey and Scott – Textbook of diagnostic microbiology. 12thed. Amsterdam, The Netherlands: Elsevier; 2007.
Gilbert DN, Moellering RC, Eliopoulos GN, Sande NA. Sanford guide to antimicrobial therapy. 32nd ed. Hyde Park, Vermont: Antimicrobial Therapy, Inc.; 2005. pp. 22–23.
This work is licensed under a Creative Commons Attribution 3.0 License.
Print ISSN: 2347-6192
Online ISSN: 2347-6206